Pascal Arnoux obtained his PhD in Structural Biology at the University of Orsay in 2000 (with Dr. M. Czjzek). After a post doctoral position at the Universiy of Toronto (with Pr. J. Rini) he obtained a researcher position at the Biosciences and Biotechnologies Institute of Aix-Marseille. His current research interests include bacterial nicotianamine-like metallophores and metalloprotein functions with a focus on structural biology.
Department of Chemistry at Barnard College, Columbia University
Rachel Narehood Austin is the Diana T. and P. Roy Vagelos Professor of Chemistry in the Department of Chemistry at Barnard College, Columbia University. Her doctoral work focused on synthetic models of high valent intermediates in the reaction cycle of cytochrome P450; work she did collaboratively with the laboratories of Alfred Trautwein in Lubeck Germany and Raymond Weiss in Strasbourg. Her laboratory has a longstanding interest in understanding the mechanisms of metalloproteins, especially those important in the global cycling of elements and neurochemistry, and developing and characterizing heterogeneous catalysts that can be used for green chemistry, biofuels upgrading, or environmental remediation.. Funding for her lab has been received from NSF, NIH, HHMI, the Merck/AAAS research fund, Pfizer, DOE, and the Dreyfus Foundation. She is the past chair (together with co-Chair Ariel Anbar) of the 2010 Environmental Bioinorganic Chemistry Gordon Research Conference and a current editorial board member of the Journal of Inorganic Biochemistry, an advisory board member for the journal Metallomics and a reviewing editor for the journal Frontiers in Microbiological Chemistry.
Department of Biophysics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw
The research conducted in Prof. Bal’s group is focused on quantitative and structural description of complexes and reactions relevant to essential metal ion homeostasis (Cu, Zn), industrial and environmental metal ion toxicology (Ni, Cd, As, Ag) and metal based processes in protein engineering. The most significant achievements include the discovery and elucidation of the reaction of Ni(II), Cu(II) and Pd(II) reaction with proteins and peptides leading to sequence-specific hydrolysis of peptide bonds. This reaction is a foundation of the proprietary methodology of purification of recombinant proteins and is also a source of new concepts in metal allergy. Other significant results include a new hypothesis on the role of specific isoforms of Aβ peptides related to Alzheimer’s disease as synaptic Cu(II) chaperons and the emerging paradigm for intracellular zinc transport by low molecular weight metabolites. Applied research conducted in his group resulted in the design and synthesis of a new copolymer which constitutes the active ingredient of a series of barrier cosmetics protecting from the symptoms of nickel allergy, which are marketed by a startup company.
Magnetic Resonance Center and Department of Chemistry, University of Florence
Lucia Banci is Professor of Chemistry at the University of Florence. Lucia Banci has a high international reputation for her original contributions and breakthroughs in Structural Biology and in biological NMR. She is recognized as a world-class leader in the characterization of functional processes in a cellular context with atomic resolution. She has addressed and unravelled many aspects of the biology of metal ions in biological systems, from their homeostasis processes to the trafficking and metal incorporation to the final receiving proteins. She developed a molecular systems biology approach which integrates structural, interaction and dynamical information with the thermodynamic properties of the processes, so as to have a unified picture of the processes responsible of metal ion trafficking, with a particular focus on copper and on the biogenesis and maturation of iron-sulfur cluster proteins. On these systems, she is developing and exploiting innovative approaches which combine standard spectroscopic techniques with paramagnetic based methods.
Over the recent years, Lucia Banci exploited the extensive knowledge of structural biology approaches by NMR to develop an absolutely innovative approach to vaccine design, which she first named «Structural Vaccinology» based on the knowledge of the structure of the pathogen antigens and of the interaction pattern with antibodies, to design structure-based vaccines. With this approach, she provided an essential contribution to the development of a vaccine against meningococcus B pathogen, which is characterized by several variants, each exhibiting different epitopes on a very effective antigen. The knowledge of the structural properties allowed the design of a chimaera antigen which has complete protectivity against all the variants.
Finally the most recent line of her research, in cell NMR, is raising a very high interest in various scientific communities, either interested in new methodological advancements in NMR or in the striking new knowledge obtained in biological processes. The innovative in cell NMR approach developed by Lucia Banci and his group allows for the detection of human individual proteins (a single one or more such as partner proteins) with atomic-level resolution in living human cells. This approach realizes the bridge between cellular studies (which maintain the cellular environment but lack atomic information) and structural characterization (which provides a detailed, atomic-level description in vitro).
She has published more than 370 research articles and has solved above 150 protein structures. (h-Index (Google Scholar) = 73)
She is one of the founders and past Director of CERM.
She is a member of EMBO, of AcademiaNet and is the Italian delegate in the Council of the European Molecular Biology Laboratory (EMBL).
She has been awarded the IUPAC Award “Distinguished Women in Chemistry” (2015) and the “Fiorino d’Oro Della Città di Firenze” Gold Medal of the City of Florence.
Department of Physical and Analytical Chemistry, University of Oviedo
Jörg Bettmer received his PhD in 1996 from the University of Münster, Germany, for his investigations on the speciation of mercury and lead (supervisor: Professor Karl Cammann). In 2000, he moved to the University of Mainz, Germany, to work in the group of Professor Klaus G. Heumann and he obtained the “habilitation” (venia legend in Analytical Chemistry) from the same university in 2004. In 2007, he started as a Ramón y Cajal researcher at the University of Oviedo, Spain. He became the assistant professor in 2012 and associate professor in 2016, resp. His research interests cover the development and application of MS-based hyphenated techniques in the fields of elemental speciation and metallomics and the analysis of metal-based nanomaterial using ICP-MS techniques.
College of Earth, Ocean, and Atmospheric sciences at Oregon State University
Dr. Boiteau is an Assistant Professor in the college of Earth, Ocean, and Atmospheric sciences at Oregon State University. His research focuses on understanding how microbes and plants impact the mobility and bioavailability of metals in marine and terrestrial environments. Through the development of analytical approaches to characterize organic metal speciation and determine their kinetic properties using chromatography coupled with multimodal mass spectrometry, his work aims to develop predictive knowledge of how metals impact biogeochemical processes.
Daniela Buccella is an Associate Professor in the Department of Chemistry at New York University. She completed her Ph.D. studies in Chemistry at Columbia University, where she worked in the group of Prof. Ged Parkin in the area of inorganic synthesis and catalysis. She then moved to the Massachusetts Institute of Technology, where she worked with Prof. Stephen Lippard on the study of zinc biology as an NIH postdoctoral fellow. Work in her research group at NYU focuses on the development of new molecular probes and imaging strategies for the study of cellular metal homeostasis, in particular that of magnesium and manganese. Prof. Buccella currently serves in the editorial advisory board of Inorganic Chemistry and has been the recipient of a Whitehead Fellowship for Junior Faculty in Biomedical and Biological Sciences, and an NSF CAREER award.
Alison Butler is Distinguished Professor of Chemistry & Biochemistry at the University of California, Santa Barbara. She obtained her PhD in mechanistic inorganic chemistry at UC San Diego and after postdoctoral fellowships with Joan Valentine at UCLA and Harry Gray at Caltech, she began her independent career at UC Santa Barbara in 1986. Her research spans a range of interests in bioinorganic chemistry and metallobiochemistry, including unusual metalloenzymes and mechanisms of acquisition of metal ions by microbes. Currently her research group is focused on genomic screening to target discovery new microbial siderophores and evolutionary developments in siderophore biosynthesis. She has served a term as President of the Society for Biological Inorganic Chemistry (SBIC) and has been elected Chair of three Gordon Research Conferences, in Marine Natural Products, Metals in Biology and Environmental Bioinorganic Chemistry. Alison Butler is Fellow of American Association for the Advancement of Science and the American Chemical Society (ACS). She is the 2018 recipient of the ACS Alfred Bader Award in Bioinorganic or Bioorganic Chemistry and a recipient of a 2019 ACS Cope Scholar Award.
Medicinal and Bioinorganic Chemistry at Cardiff University (UK)
Angela Casini is Chair of Medicinal and Bio-inorganic Chemistry at Cardiff University (UK) since 2015. She completed her PhD in Chemistry at the University of Florence (Italy) in 2004, and, afterwards, moved to EPFL (Switzerland) as senior scientist funded by the Swiss National Science Foundation. Between 2011-2015 she has been the assistant professor at the University of Groningen (The Netherlands), holding a Rosalind Franklin Fellowship, before taking up her current position at Cardiff University. She was awarded the 2012 European Medal for Biological Inorganic Chemistry and, in 2014, she has been listed by Thomson Reuters as one of the “World’s most influential scientific minds” in the field of Pharmacology. Since 2016 she is also Hans Fischer Senior Fellow of the prestigious Institute of Advanced Study of the Technical University of Munich. Her research focuses on the study of the role of metal ions in biological systems and of the mechanisms of action of metal-based anticancer agents. Furthermore, novel applications for metal-based compounds and supramolecular coordination complexes are explored in various domains of chemical biology, drug delivery and physiology. In these fields, she is the author of more than 200 publications.
Debbie C. Crans is a Professor of Organic, Inorganic and Biological Chemistry and of Cell and Molecular Biology at Colorado State University where she was Professor Laureate of the College of Natural Sciences (2015-2017). She did her undergraduate studies in Denmark in Biochemistry and Physical Organic Chemistry, her Ph.D. in Chemistry at Harvard University and postdoctoral studies at University of California, Los Angeles. She founded the International Vanadium Symposium and Vanadium Society, ran the Metals in Medicine Gordon Conference, initiated the coordination chemistry branch of programming at the National ACS meetings, ran four Zing Coordination Chemistry Conferences, and in 2022 she will chair the International Coordination Chemistry Conference (ICCC-45) in Colorado. She is on the executive board of the Inorganic Division of the American Chemical Society. She is associate editor of the Royal Society of Chemistry’s New Journal of Chemistry and of Elseviers Coordination Chemistry Reviews. She received the ACS Award for Distinguished Service in the Advancement of Inorganic Chemistry in 2019, the Cope Scholar Award in 2015, the Vanadis Award in 2004, an Alexander von Humboldt Senior Research Award in 2001 and have also received recognitions by the Colorado Section of ACS and Colorado State University for her research, teaching, mentoring and service to various communities. Her research interests are in the areas of organic and inorganic drugs and their targets, metals in medicine, electron transfer processes at membranes, membranes and model membrane systems, micelles and reverse micelles, coordination chemistry and spectroscopy. She works on diseases such as cancer, tuberculosis, Alzheimer’s and diabetes.
Biological Inorganic Chemistry, University of York
Anne-Kathrin Duhme-Klair obtained her PhD in Inorganic Chemistry at the University of Oldenburg in 1992 (with Prof. Siegfried Pohl and Dr. Henry Strasdeit). After postdoctoral positions at King’s College London (with Prof. Robert C. Hider) and the EMBL Outstation at DESY in Hamburg, she completed her Habilitation at the University of Münster (with Prof. Bernt Krebs). In 1998, she was appointed to a lectureship in Biological Inorganic Chemistry at the University of York, where she is now a Professor in Inorganic Chemistry. Her current research interests include siderophore-mediated iron uptake, molybdoenzyme mimics and the development of new antimicrobials.
Institut de Chimie, Université de Strasbourg, France
Peter Faller is Professor in Chemistry at the University of Strasbourg (F) and Group Leader at the Institute of Chemistry (UMR 7177). He studied at the University of Zürich (CH) earning a PhD in biochemistry on metallothioneins with M. Vasak. He did his postdoctoral studies on photosystem II at the CEA near Paris (F) and in Freiburg (D). He was Professor and group leader for a decade at the Laboratory for Coordination Chemistry (LCC) in Toulouse (F) before moving to Strasbourg in 2015.
Research interest: Structure of metal-peptide/protein complexes; Metal transfer between peptides/proteins and between metal-drugs and proteins; Self-assembly of amyloidogenic peptides into amyloid fibrils and effect of metal ions, chaperons, inhibitors, etc., Fluorescent molecules and techniques to monitor the self-assembly process and/or metal-binding; Chemical reactivity of metal-complexes, in particular towards generation of reactive oxygen species.
Katherine J. Franz is the Alexander F. Hehmeyer Professor and Chair of Chemistry at Duke University in Durham, North Carolina, USA. As an undergraduate she conducted research with Prof. James Loehlin at Wellesley College and Dr. Richard Fish at the Lawrence Berkeley National Lab. She obtained her PhD in inorganic chemistry with Prof. Stephen J. Lippard at MIT, and completed an NIH postdoctoral fellowship with Prof. Barbara Imperiali, also at MIT. Since 2003, Kathy and her research group at Duke focus on elucidating the structural and functional consequences of metal ion coordination in biological systems, both by endogenous species and by synthetic molecules of their own design. They are particularly interested in understanding the coordination chemistry of essential yet toxic species like copper and iron, and using these principles to guide the development of new chemical tools to manipulate the location, speciation, and reactivity of metal ions in complex and dynamic environments like those found in biological systems.
David Giedroc earned degrees from the Pennsylvania State University and Vanderbilt University and was a member of the faculty of Biochemistry and Biophysics at Texas A&M University from 1988-2007. He was appointed Professor of Chemistry at Indiana University in 2007, served as Chair of Department from 2010-2015 and was named Lilly Chemistry Alumni Professor in 2015. Prof. Giedroc is a Fellow of the AAAS, the Royal Society of Chemistry and the American Academy of Microbiology, and currently serves as Chair of the Editorial Board of Metallomics. Prof. Giedroc’s research interests span the biophysical chemistry of infectious disease, with a focus on transition metallostasis and hydrogen sulfide sensing and reactive sulfur species (RSS) in major bacterial pathogens.
School of Chemistry and Chemical Engineering of Nanjing University
Zijian Guo is a Chang Jiang professor at the State Key Laboratory of Coordination Chemistry in the School of Chemistry and Chemical Engineering of Nanjing University. He was elected to the fellow of the Chinese Academy of Sciences in 2017. He was awarded the First Prize in Natural Sciences from Ministry of Education of China in 2015, the Luigi Sacconi Medal from the Italian Chemical Society in 2016. His major research interest focuses on the design and application of fluorescent sensors for bio-related metal cations, and the design, mechanistic studies and targeted delivery of metal-based anti-tumor complexes.
Christian Hartinger studied chemistry at the University of Vienna and received his PhD there in 2001 under B. K. Keppler. He was an Erwin Schrödinger Fellow with P. J. Dyson at the École Polytechnique Fédérale de Lausanne (EPFL) from 2006 to 2008, did his habilitation at the University of Vienna in 2009 and accepted an Associate Professorship at the University of Auckland in 2011 where he was promoted Professor in 2015. His research focuses on the development of metal-based anticancer agents and of analytical methods to characterize their behavior in presence of biomolecules. He has published more than 185 original papers and reviews (h-index 57, > 10,600 citations). His work earned him several awards including the 2011 Carl Duisberg Memorial Prize, the 2016 Society of Biological Inorganic Chemistry Early Career Award, the 2016 New Zealand Institute of Chemistry Chemical Science Prize and the 2017 Hill Tinsley Medal by the New Zealand Association of Scientists.
Bin Hu received his Ph.D. degree from Wuhan University in 1992 and was a visiting scholar/postdoc research associate at Clemson University during 1996-1997. Currently, he is a professor at Wuhan University. He has published over 350 scientific papers as well as 5 books, and has 15 patents. His research interests are ICP-MS based strategies for biomedical analysis, elemental speciation, sample pretreatment techniques, metal-containing nanoparticles detection and their biosafety. He received numerous scientific awards including the Natural Science Prize and New Century Excellent Talents from MOE of China, and Natural Science Prize and Outstanding Young Scientist Prize from Hubei Province, China.
Norbert Jakubowski is head of the division „Inorganic Trace Analysis“ at BAM. He studied physics at the University of Essen/Duisburg and received his PhD at the University of Stuttgart Hohenheim in 1991. In 2013 he received the ‘‘European Award for Plasma Spectrochemistry’’ for his contribution in elemental mass spectrometry. His research interests are related to Analytical Chemistry, development of instruments and analytical methods for application in the „Life Sciences“.
Uwe Karst was Full Professor of Chemical Analysis at the University of Twente in the Netherlands between 2001 and 2005, before he accepted his current position as Chair of Analytical Chemistry at the University of Münster in Germany in 2005. His research interests focus on hyphenated analytical techniques and their (bio)medical and pharmaceutical applications, including elemental speciation analysis, metallomics, mass spectrometric imaging and electrochemistry/MS.
Yaichiro Kotake obtained his Ph.D. from Graduate School of Pharmaceutical Sciences, the University of Tokyo (Japan) in 1998. He moved to Hiroshima University and worked as a post-doctoral fellow, a research associate, and an associate professor. He was appointed as a full professor at Hiroshima University in 2018. His research focuses on the neurotoxicity of organometals and the environmental factors in brain disease such as Parkinson’s disease.
Christian Kowol is currently Assistant Professor (tenure track position) at the University of Vienna. He studied chemistry at the University of Vienna and finished his PhD in the area of Inorganic
Chemistry in 2009. The research of Christian Kowol focuses on interdisciplinary studies in the area of metal-based anticancer drug design: mainly prodrug development, drug delivery systems and peptide targeting strategies to increase activity and tolerability of cancer drugs. He is active member of the Comprehensive Cancer Center of the Medical University of Vienna and was honored in the last years with several awards.
The founder of Polish bioinorganic chemistry, currently working at the interface between chemistry and biology. At the Department of Chemistry, University of Wroclaw, he created one of the most dynamic research teams – the Bioinorganic and Biomedical Chemistry group. Visiting Professor at the Universities of Strasbourg, Siena, Ferrara, Florence, Sassari, Cagliari, Lille, Dunkirk and Paris. He has supervised 37 PhDs. Scientific achievements: Hirsch index of 46, over 530 original papers, 17 book chapters, over 500 conference speeches and over 400 invited lectures given at international and national conferences and at various universities. Cited more than 11000 times. From 2016 Ordinary Member of the Polish Academy of Sciences. Doctor Honoris Causa of the University of Gdańsk and Doctor Honoris Causa of the National Taras Shevchenko University in Kiev, Ukraine. Honorary Professor of Wroclaw University of Technology. Fellow of the Royal Society of Chemistry (CSc, FRSC).
Department of Nutrition and Dietetics, King’s College, London
Professor, King’s College London, 2009 (Biochemistry and Nutritional Sciences Department)
Associate Professor, The University of Texas Medical Branch, Galveston, TX, USA 2002-2009
Assistant Professor, Harvard Medical School, Boston, MA, USA 1986-2002
Research Associate, Saarland University, Saarbrucken, Germany 1982-1986
Postdoctoral Research Fellow, The University of Chicago, Chicago, IL, USA 1980-1982
Molecular and cellular mechanisms of metal homeostasis
Role of micronutrients in normal physiology and pathophysiology
Sulfur and selenium redox biochemistry
Structure and function of metalloenzymes
Key words: Transition Metals, Zinc, Iron, Selenium, Redox Stress, Redox Signaling, Metallothionein, Alcohol Dehydrogenases, Glutathione, Polyols, Carotenoids and Retinoids, Cellular Injury and Repair, Diabetes
Elizabeth M. Nolan is an Associate Professor of Chemistry at MIT. She pursued her graduate studies with Professor Stephen J. Lippard at MIT and her post-doctoral studies with Professor Christopher T. Walsh at Harvard Medical School. Her current research interests address the chemistry and biology of human innate immunity and microbial pathogenesis. Her lab employs the toolkits of biological chemistry, inorganic chemistry, and microbiology to decipher the interplay between the human innate immune system and microbes, and to conceptualize and evaluate new strategies for preventing and treating microbial infections.
Clotilde Policar a professor in bio-inorganic chemistry at the Ecole Normale Supérieure in Paris. After a Ph.D. at Paris-Sud 11 and Paris 5 universities on mimics of a metalloprotein, she worked as a post-doctoral fellow on high-field electron paramagnetic resonance to characterize complexes mimicking the Mn cluster from the oxygen evolving center in the photosystem II. She was then appointed assistant professor at Paris-Sud 11, where she focused on the development of Mn-complexes mimicking the manganese superoxide-dismutase (SOD). Since 2008, she has a professorship at the Ecole Normale Supérieure, where she has set up a thematic group in inorganic cellular and biological chemistry. She works on the design and evaluation in cells of metal complexes mimicking metalloenzymes such as SOD. Her group also develops metalloprobes as multimodal probes for original imaging, including IR and X-fluorescence imagings. She is a current editorial board member of the Journal of Inorganic Biochemistry, a former advisory board member for the ACS Inorganic Chemistry. Clotilde Policar is presently the dean of the studies at the department of chemistry of ENS and she is also a scientific delegate at the institute of chemistry (INC) of CNRS involved in the development of interdisciplinarity.
David Salt is a Professor of Genome-Enabled Biology in the School of Biosciences. His research focuses on the molecular mechanisms that plants use to take up and accumulate the essential mineral nutrients that they need for normal growth and development. He is also interested in how plants mistakenly accumulate potentially toxic trace elements such as cadmium and arsenic. These issues are important for agriculture, human health as plants are a major source of dietary mineral and food safety due to the accumulation of potentially toxic trace elements in food.
Professor Salt is also the academic lead for the University’s Future Food Beacon of Excellence which addresses the challenge of feeding a growing population in a changing world.
The Future Food Beacon brings together expertise from across the food chain – from soil to molecule to meal – to deliver sustainable solutions to global food challenges such as ‘hidden hunger’: less diverse diets, naturally low nutrients in our staple crops, and an increasing reliance on over-processed foods mean that more than a quarter of the world population are not getting the goodness they need from what they eat.
Institute of Nutritional Science, University of Potsdam
Tanja Schwerdtle is chair of the Department of Food Chemistry in the Institute of Nutritional Science at the University of Potsdam. The Schwerdtle group has many years of research experience in the field of the toxicity of metal(loid) compounds. Predominantly, team Schwerdtle focuses on the molecular mechanisms of metal(loid) species induced carcinogenicity and neurotoxicity, investigating the impact of toxic metal(loid) species but also TE species (especially Mn2+, Cu2+ as well as inorganic and organic Se species) on DNA damage response and DNA repair pathways. Moreover, the group is very experienced and internationally recognized in the field of metal(loid) analysis in biological samples by the use of state of the art instrumental techniques including ICPMSMS. In this context, the team has successfully established new test systems to assess ADME, indirect genotoxicity, epigenetic as well as stress related effects. The combined use of their instrumental analytical and toxicological testing expertise enables the group to contribute efficiently to TraceAge especially by reliably quantifying the TE profiles and species in all human, mouse and C. elegans samples as well as by studying these effects in the context of genomic instability, epigenetics and aging. In the BMBF-funded competence cluster NutriAct “Nutritional Intervention for Healthy Aging: Food Patterns, Behavior and Products” Tanja Schwerdtle actually coordinates 10 groups in the field of biomarker research, providing the possibility to interpret the outcome of the NutriAct intervention study also in the context of TE and aging.
Anatoly V. Skalny, MD, PhD, DSc, Professor, has completed his PhD at the age of 28 years from All-Union Centre for Narcology, Moscow. He has published more than 600 journal articles, abstracts, book chapters and guidelines in English and Russian. Prof. Skalny is a specialist in trace element research in medicine and biology. His main research interests include the investigation of the role of trace elements in neuropsychiatric and endocrine disorders, reactions of the organism to various stressors, as well as demography and population health. Professor Skalny is a vice-president of Trace Element Institute for UNESCO (Lyon, France), the chairman of Russian Society of Trace Elements in Medicine, a vice-president of the Federation of European Societies on Trace Elements and Minerals (FESTEM). He is the Head of the Department of Medical Elementology of the Medical Institution of RUDN University (Moscow, Russia). Prof. Skalny is a member of editorial board of Journal of Trace Elements in Medicine and Biology (Elsevier), Biological Trace Element Research (Springer), the Editor-in-Chief of the journal Trace Elements in Medicine (Moscow), a member of editorial board of the journal Issues of Biological, Medicinal and Pharmaceutical Chemistry (Russia).
Skalny, A. V., Skalnaya, M. G., Nikonorov, A. A., & Tinkov, A. A. (2016). Selenium Antagonism with Mercury and Arsenic: From Chemistry to Population Health and Demography. In: Selenium: Its Molecular Biology and Role in Human Health (Hatfield DL, Schweizer U, Tsuji PA, Gladyshev VN, eds.) (pp. 401-412). Springer International Publishing.
Skalny, A. V., Simashkova, N. V., Klyushnik, T. P., Grabeklis, A. R., Radysh, I. V., Skalnaya, M. G., Tinkov, A. A. (2016). Analysis of Hair Trace Elements in Children with Autism Spectrum Disorders and Communication Disorders. Biol Trace Elem Res, 177(2):215-223.
Skalny AV, Simashkova NV, Klyushnik TP, Grabeklis AR, Radysh IV, Skalnaya MG, Nikonorov AA, Tinkov AA. (2017) Assessment of serum trace elements and electrolytes in children with childhood and atypical autism. J Trace Elem Med Biol. 43:9-14
Skalny, A. V., Klimenko, L. L., Turna, A. A., Budanova, M. N., Baskakov, I. S., Savostina, M. S., … & Tinkov, A. A. (2017). Serum trace elements are associated with hemostasis, lipid spectrum and inflammatory markers in men suffering from acute ischemic stroke. Metab Brain Dis, 32(3):779-788
Skalny, A. V., Simashkova, N. V., Klyushnik, T. P., Grabeklis, A. R., Bjørklund, G., Skalnaya, M. G., Nikonorov A.A., Tinkov, A. A. (2016). Hair toxic and essential trace elements in children with autism spectrum disorder. Metab Brain Dis, 32 (1):195-202
Skalny, A. V., Klimenko, L. L., Turna, A. A., Budanova, M. N., Baskakov, I. S., Savostina, M. S., Mazilina, A.M., Deyev A. I., Skalnaya M. G., Tinkov, A. A. (2017). Serum trace elements are interrelated with hormonal imbalance in men with acute ischemic stroke. J Trace Elem Med Biol. 43:142-147
Aaseth, J., Ajsuvakova, O. P., Skalny, A. V., Skalnaya, M. G., & Tinkov, A. A. (2018). Chelator combination as therapeutic strategy in mercury and lead poisonings. Coord Chem Rev, 358, 1-12.
Tinkov, A. A., Gritsenko, V. A., Skalnaya, M. G., Cherkasov, S. V., Aaseth, J., & Skalny, A. V. (2018). Gut as a target for cadmium toxicity. Environ Poll, 235, 429-434.
Olechnowicz, J., Tinkov, A., Skalny, A., & Suliburska, J. (2017). Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism. J Physiol Sci, 68(1):19-31
Bjørklund G, Aaseth J, Ajsuvakova OP, Nikonorov AA, Skalny AV, Skalnaya MG, Tinkov AA (2017) Molecular Interaction between Mercury and Selenium in Neurotoxicity. Coord Chem Rev, 332, 30-37
Michael Sperling is Chief Managing Director of the European Virtual Institute for Speciation Analysis (EVISA) at the University of Muenster, Germany. His reaserch interests include the development of robust methods for speciation analysis, the automation of analytical methods by the use of flow techniques and the development of plasma sources for atomic and mass spectrometry.
PROFESSIONAL EXPERIENCE:• 07/2007- Present: Professor, Department of Chemistry, University of Hong Kong
• 12/1998- 06/2007 Assistant and Associate Professor, Department of Chemistry, University of Hong Kong
• 10/1996-12/1998: GlaxoWellcome Research Fellow, Department of Chemistry, the University of Edinburgh, UK
• 10/1993~ 09/1996: Ph.D. Study, Bioinorganic Chemistry, the University of London, UK
• 08/1990~ 09/1993: Research Associate and Lecturer, Coordination Chemistry Institute, Nanjing University, Nanjing, P.R. China
Biological Inorganic Chemistry; Structural Biology of Metalloproteins; Metallomics & metalloproteomics
REPRESENTATIVE PUBLICATIONS: (Over 120 publications)
1. Xia W., Li H.Y., Yang X.M., Wong K.B., Sun HZ* (2012) “Metallo-GTPase HypB from Helicobacter pylori and its interaction with nickel chaperone protein HypA” Journal of Biological Chemistry, 287(9), 6753-6763.
2. Li H.Y., Sun HZ (2012) “Recent advances in bioinorganic chemistry of bismuth” Current Opinion in Chemical Biology 16, 74-83.
3. Tsang CN, Ho KS, Sun HZ*, Chan WT (2011) “Tracking bismuth drug uptake in single Helicobacter pylori cells” Journal of the American Chemical Society, 133(19), 7355-7357.
4. Wang XH, Du XB, Li HY, Chan DSB, Sun HZ* (2011) “The effect of the extracellular domain of human copper transporter (hCTR1) on cisplatin activation” Angewandte Chemie International Edition, 50, 2706-2711. (Frontispiece)
5. Sun HZ (editor), “The biological chemistry of arsenic, antimony and bismuth”, John Wiley& Sons, 2011.
6. Cun SJ, Sun HZ* (2010) “A zinc binding site by negative selection induces metallodrug susceptibility of an essential chaperonin” Proceedings of the National Academy of Sciences, USA, 107, 4943-4948.
7. Xia W, Li HY, Sze KH, Sun HZ* (2009) “Structure of a nickel chaperone, HypA from Helicobacter pylori reveals two distinct metal binding sites” Journal of the American Chemical Society, 131, 10031-10040.
Frank Vanhaecke is Professor in Analytical Chemistry at Ghent University, Belgium. He leads the ‘Atomic & Mass Spectrometry A&MS’ research group that studies fundamentally-oriented aspects of ICP-MS and develops methods for solving challenging problems in an interdisciplinary context. Specific topics are the direct analysis of solid materials by means of LA-ICP-MS, HPLC-ICP-MS speciation strategies for pharmaceutical applications and isotopic analysis using MC-ICP-MS. Frank is (co-)author of ~300 journal papers. In 2011 he received a “European Award for Plasma Spectrochemistry”.
Chalmers University of Technology, Gothenburg, Sweden
Pernilla Wittung-Stafshede obtained a PhD in Physical Chemistry 1996, at Chalmers University of Technology, Gothenburg, Sweden. During 1997-1998 she did a postdoc at the Beckman Institute at California Institute of Technology, Pasadena, California, USA with Harry Gray. In 1999 she started her independent career as an assistant professor in Chemistry at Tulane University, New Orleans, Louisiana, USA. She received tenure and was promoted to associate professor in 2002. In 2004 she moved to Rice University, Houston, Texas, USA, as associate professor with tenure in the Biochemistry and Cell Biology department. After 5 years, in 2008, she returned to Sweden and became full professor in Chemistry at Umeå University in the north of Sweden. She spent 7 years there before moving to Gothenburg in 2015 to the newly-founded Biology and Biological Engineering department, there acting as head of one of its divisions, Chemical Biology. Her research centres around protein biophysics, with current focus on mechanisms of copper transport proteins and cross-reactivity in amyloid formation. She was elected into the Royal Swedish Academy of the Sciences in 2016 and last year she was elected member of the Biophysical Society Council. She has published over 200 peer-reviewed papers on the topics related to protein function.